Title : Evaluation of the toxicity of copper oxide and nanoparticles using the biochemical, hematological, and histological biomarkers in Nile tilapia, (Oreochromis niloticus)
Abstract:
This study aims to evaluate the toxicity of synthesized copper nanoparticles (CuO-NPs) on biochemical and histological changes in Nile tilapia. Silver nanocolloids were characterized using visible and ultraviolet light spectroscopy and high-resolution transmission electron microscopy (HRTEM). The results show that the exposure of Oreochromisniloticus to CuO-NPs (0.525 mg/L) at pH 7, 15 °C and 25 °C showed a significant decrease in the values of RBCs, hemoglobin, hydrogen, MCV, MCH and MCHC but a significant increase in WBCs The histological changes and apparent damage to the gills were more than the control group and the other treatments exposed to the same concentration of CuO-NPs at a higher pH (9) and salinity (34 ppm) which showed normal values. Hence it is recommended to reduce the toxicity of CuO-NPs in Oreochromis niloticus fish farms by increasing the water pH to 9 or increasing the water salinity.
Keywords: CuO-NPs toxicity, Oreochromis niloticus, blood parameters.
