Managing disease is a critical aspect of aquaculture, as infections can spread rapidly in densely populated water environments. Effective disease management includes monitoring water quality, ensuring proper nutrition, and implementing biosecurity protocols to prevent the introduction of pathogens. Vaccination and probiotic use can help boost immunity, while quarantine practices are essential for introducing new stocks. Technology, such as real-time sensors and diagnostic tools, assists in detecting health issues early, allowing for rapid response to prevent widespread outbreaks. By prioritizing disease management, aquaculture operations can maintain healthier stocks, improve yield, and reduce reliance on antibiotics, fostering a more sustainable aquaculture industry.